English
norskBlar i forfatter "Olsen, Karina"
Viser treff 1-13 av 13
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Age- and Gender-Associated Staphylococcus aureus spa Types Found among Nasal Carriers in a General Population: the Tromsø Staph and Skin Study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)Staphylococcus aureus nasal carriers risk autoinfection; however, knowledge about the factors that make specific strains successful colonizers is limited. This study was undertaken to identify the most successful S. aureus clones in nasal carriers and compare their distribution among host groups. The population structure of S. aureus isolates from healthy adults was investigated by spa typing 1,981 ... -
Circulating sex-steroids and Staphylococcus aureus nasal carriage in a general female population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02)<p>Objective: <i>Staphylococcus aureus</i> is a major human pathogen, and nasal carriers have an increased risk for infection and disease. The exploration of host determinants for nasal carriage is relevant to decrease infection burden. Former studies demonstrate lower carriage prevalence in women and among users of progestin-only contraceptives. The aim of this study was to investigate the possible ... -
Circulating sex-steroids and Staphylococcus aureus nasal carriage in a general male population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-22)Male sex is associated with higher risk of both colonisation and infection with Staphylococcus aureus (S. aureus). However, the role of sex-steroids in colonisation among men is largely unknown. Thus, the aim of this study was to investigate possible associations between circulating sex-steroids and nasal carriage of S. aureus in a general male population. The population-based Tromsø6 study (2007–2008) ... -
Clinical course, treatment and visual outcome of an outbreak of Burkholderia contaminans endophthalmitis following cataract surgery
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-19)Background - Postoperative endophthalmitis is a rare but dreaded complication of intraocular surgery and often results in severe visual impairment or blindness. The present study describes the clinical course, treatment and visual outcome of an outbreak of Burkholderia contaminans endophthalmitis following cataract surgery.<p> <p>Methods - Among 290 patients who underwent uneventful phacoemulsification ... -
Elevated odds of metabolic syndrome in psoriasis: A population-based study of age and sex differences
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-07-24)Background Questions remain concerning to what extent age and sex may modify the suggested association between psoriasis and the metabolic syndrome in the general population. Objectives To investigate the association between psoriasis and the metabolic syndrome within a large population-based cohort by age and sex.<p> <p>Methods A cross-sectional study including 10 521 participants aged 30–79 ... -
Emergence of vancomycin-resistant enterococci from vancomycin susceptible enterococci in hospitalized patients under antimicrobial therapy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-19)Objectives: Enterococci are opportunistic pathogens with plastic genomes that evolve, acquire, and transmit antimicrobial-resistant determinants such as vancomycin resistance clusters. While vancomycinresistant enterococci (VRE) have emerged as successful nosocomial pathogens, the mechanism by which vancomycin-susceptible enterococci (VSE) transform to VRE in hospitalized patients remains ... -
Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-05)<i>Background</i>: Use of hormonal contraceptives has been associated with <i>Staphylococcus aureus</i> nasal carriage in adult women. However, the role of hormonal contraceptives in S. aureus colonization among adolescents and associations with progestin only contraceptives are unknown.<p> <p><i>Methods</i>: We obtained nasal and throat swab samples from 439 girls aged 17–21 years in the ... -
Obesity and Staphylococcus aureus Nasal Colonization among Women and Men in a General Population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Background: Obesity and diabetes mellitus (DM) have been linked to increased risk of infections, and Staphylococcus aureus nasal colonization is a major risk factor for developing infections with the microbe. We therefore sought to find whether body mass index (BMI) and waist circumference (WC) could be associated with S. aureus colonization independent of DM. Methodology: S. aureus colonization ... -
Prevalence and population structure of Staphylococcus aureus nasal carriage in healthcare workers in a general population. The Tromsø Staph and Skin Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Healthcare workers (HCWs) may be a reservoir for Staphylococcus aureus transmission to patients. We examined whether HCW status is associated with S. aureus nasal carriage and population structure (spa types) in 1302 women (334 HCWs) and 977 men (71 HCWs) aged 30–69 years participating in the population-based Tromsø Study in 2007–2008. Multivariable logistic regression models were used. While no ... -
Social network analysis of Staphylococcus aureus carriage in a general youth population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-31)Objectives Staphylococcus aureus carriage increases infection risk. We used social network analysis to evaluate whether contacts have the same S. aureus genotype indicating direct transmission, or whether contagiousness is an indirect effect of contacts sharing the same lifestyle or characteristics. Methods The Fit Futures 1 study collected data on social contact among 1038 high school students. ... -
Staphylococcus aureus nasal carriage is associated with serum 25-hydroxyvitamin D levels, gender and smoking status. The Tromso Staph and Skin Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)Vitamin D induces the expression of antimicrobial peptides with activity against Staphylococcus aureus. Thus, we studied the association between serum 25-hydroxyvitamin D (25(OH)D) and S. aureus nasal colonization and carriage. Nasal swabs, blood samples and clinical data from 2,115 women and 1,674 men, aged 30–87 years, were collected in the Tromsø Staph and Skin Study 2007–08, as part of the ... -
Staphylococcus aureus nasal carriage is associated with serum 25-hydroxyvitamin D levels, gender and smoking status. The Tromsø Staph and Skin Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)Vitamin D induces the expression of antimicrobial peptides with activity against Staphylococcus aureus. Thus, we studied the association between serum 25-hydroxyvitamin D (25(OH)D) and S. aureus nasal colonization and carriage. Nasal swabs, blood samples and clinical data from 2,115 women and 1,674 men, aged 30–87 years, were collected in the Tromsø Staph and Skin Study 2007–08, as part of the ... -
Staphylococcus aureus nasal carriage – Interplay between host, microbe and the environment
(Doctoral thesis; Doktorgradsavhandling, 2013-09-20)Background: S. aureus colonizes persistently 20–30% of the adult human population (S. aureus carriers), and can also cause serious infections. The main objectives of this thesis were to investigate whether the modifiable risk factors such as serum vitamin D levels and obesity, and environmental factors such as current smoking, being a healthcare worker and residing with children were associated ...
